Abstract: Folding of proteins into their active 3D-structure occurs spontaneously or is assisted with the help of chaperones within a biologically reasonable time, from micro- to milliseconds.

Abstract: The Amack Lab has a long-standing interest in understanding organ morphogenesis during embryonic development.

Abstract: The goal of cell division is to segregate genetic material, in the form of chromosomes, equally into the two daughter cells.

Abstract: Understanding the function of glutamate transporters has broad implications for explaining how neurons integrate information and relay it through complex neuronal circuits.

Abstract: Cells must complete intricate mechanical tasks during a wide variety of biological processes ranging from the segregation of chromosomes during mitosis to forming and maintaining the axon and dendrites in neurons.

Abstract: Much remains unknown about the underlying molecular mechanisms that cause insulin resistance at the center of the current pandemic of obesity, metabolic syndrome, and type 2 diabetes.

Abstract: Probing individual biomolecules such as proteins and nucleic acids with force continues to shape our understanding of how biological molecules stretch, deform, move, reconfigure, and interact with each other.

Abstract: Biodiversity loss from the rising severity of emerging infectious diseases has coincided with unprecedented rates of ecological change.

Abstract: Profilin-1 (PFN1) and TDP-43 are two proteins that have been linked to the neurodegenerative disease amyotrophic lateral sclerosis (ALS).